Region C is home to Roodepoort and much of its surrounding developments in Johannesburg's centre and north, with areas such as Florida to the southeast and Bramfischerville to the south. It is well linked to the rest of the city with major roads, such as Main Reef Road, Ontdekkers Road, Beyers Naude Drive and Malibongwe Drive. It is also conveniently situated for access to leading Gauteng attractions, such as the Cradle of Humankind, Magaliesberg and Pilanesberg.  

The suburbs in the north of Roodepoort are among the most attractive residential areas in the City, with houses dotted along rolling hills offering good views of the City to the east and Magaliesberg to the west.  There are plenty of open spaces, golf courses and entertainment areas, as well as Little Falls Resort and The Walter Sisulu National Botanical Garden.  

Region C is also home to two universities – The University of South Africa's Florida campus and the IIE MSA, formerly known as Monash South Africa, in Ruimsig. It is well-served by amenities, including shopping centres, schools, a museum and theatre, health facilities, country lodges, restaurants, sporting facilities and nature trails. 

The south western parts of the Region consist of mainly underdeveloped areas which need specific intervention initiatives. In addition, the Region also has a number of informal settlements that likewise require dedicated attention to improve the lives of the residents. Although most of these areas do receive basic services, much still has to be done to augment the services. The current infrastructure improvement initiatives in areas such as Doornkop, Bram Fischerville, Zandspruit, Matholesville, Tshepisong are geared at upgrading services and lives of the people in these communities. 

Furthermore, the first integrated housing development project, Cosmo City, is also situated within the boundaries of Region C.  

Region C is located on the northern side of Greater Soweto (Region D) and bordering Mogale City Local Municipality in the west. In the north and east it shares boundaries with Midrand (Region A) and to the east with largely prosperous residential areas of Northcliff/ Randburg and Sandton at Regions B and E respectively.  

Region C consists of the following 18 wards: 44, 49, 50, 70, 71, 83, 84, 85, 89, 97, 100, 101, 114, 126, 127, 128, 129 and 134. In addressing the City’s problem statement of inequality and illiteracy amongst others the region has a large number of public schools, independent schools and schools for learners with special needs. Tertiary institutions located within the regions consist of UNISA, IIE MSA, South-West Gauteng College, Boston College and numerous private colleges.  

Key programmes implemented in Region C are the integrated basic service delivery operations such as High Impact Service Delivery, area-based management, citizen engagement and by-law enforcement drives.